Provides an interface to the FOX GUI library. [Open Source, LGPL]

Python meta widgets is a toolkit for building high-level compound widgets in Python using the Tkinter module. [Open Source, MIT license]

A set of Python extension modules designed for writing games. The core of pygame is wrapped on top of the SDL library. [Open Source, LGPL]

The goal of this project is to create an easy-to-use, simple, and generic module for making graphical user interfaces in Python. [Open Source, MIT license]

Python bindings for the KDE desktop environment. [GPL]

The Tk Interface eXtension is a set of GUI components that enhance the appearance and functionality of your Tkinter applications. [Open Source, BSD-like]

A wrapper for the Xdialog program that encapsulates the details of calling Xdialog and getting return values. [Open Source, LGPL]

Python bindings for the GTK widget set. [Open Source, LGPL]

Contains Python bindings for the Qt GUI toolkit. [Open Source, BSD-like]

Pure Python interface to X Window system. [Open Source, GPL]